Mitochondrial genomes of Trichinella species and genotypes – a basis for diagnosis, and systematic and epidemiological explorations

Int J Parasitol. 2014 Dec;44(14):1073-80. doi: 10.1016/j.ijpara.2014.08.010.


In the present study we sequenced or re-sequenced, assembled and annotated 15 mitochondrial genomes representing the 12 currently recognised taxa of Trichinella using a deep sequencing-coupled approach. We then defined and compared the gene order in individual mitochondrial genomes (14 to 17.7 kb), evaluated genetic differences among species/genotypes and re-assessed the relationships among these taxa using the mitochondrial nucleic acid or amino acid sequence data sets. In addition, a rich source of mitochondrial genetic markers was defined that could be used in future systematic, epidemiological and population genetic studies of Trichinella. The sequencing-bioinformatic approach employed herein should be applicable to a wide range of eukaryotic parasites.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • DNA, Helminth / chemistry
  • DNA, Helminth / genetics
  • DNA, Mitochondrial / chemistry
  • DNA, Mitochondrial / genetics
  • Genome, Helminth / genetics*
  • Genome, Mitochondrial / genetics*
  • Molecular Sequence Annotation
  • Molecular Sequence Data
  • Phylogeny
  • Polymerase Chain Reaction
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Trichinella / classification
  • Trichinella / genetics*


  • DNA, Helminth
  • DNA, Mitochondrial

Associated data

  • GENBANK/KM357408
  • GENBANK/KM357409
  • GENBANK/KM357410
  • GENBANK/KM357411
  • GENBANK/KM357412
  • GENBANK/KM357413
  • GENBANK/KM357414
  • GENBANK/KM357415
  • GENBANK/KM357416
  • GENBANK/KM357417
  • GENBANK/KM357418
  • GENBANK/KM357419
  • GENBANK/KM357420
  • GENBANK/KM357421
  • GENBANK/KM357422