Planar cell polarity: the importance of getting it backwards

Curr Biol. 2014 Sep 22;24(18):R835-R838. doi: 10.1016/j.cub.2014.08.008.

Abstract

The core and Fat-Dachsous signaling systems locally align planar cell polarities in Drosophila epithelia. Three recent papers address how coupling between these systems can be altered and reversed by the products of the gene prickle.

Publication types

  • Comment

MeSH terms

  • Animals
  • DNA-Binding Proteins / genetics*
  • Drosophila Proteins / genetics*
  • Drosophila melanogaster / physiology*
  • Gene Expression Regulation, Developmental*
  • LIM Domain Proteins / genetics*
  • Signal Transduction*
  • Wings, Animal / physiology*

Substances

  • DNA-Binding Proteins
  • Drosophila Proteins
  • LIM Domain Proteins
  • pk protein, Drosophila