Improving the outcomes in oncological colorectal surgery

World J Gastroenterol. 2014 Sep 21;20(35):12445-57. doi: 10.3748/wjg.v20.i35.12445.

Abstract

During the last several decades, colorectal cancer surgery has experienced some major perioperative improvements. Preoperative risk-assessment of nutrition, frailty, and sarcopenia followed by interventions for patient optimization or an adapted surgical strategy, contributed to improved postoperative outcomes. Enhanced recovery programs or fast-track surgery also resulted in reduced length of hospital stay and overall complications without affecting patient safety. After an initially indecisive start due to uncertainty about oncological safety, the most significant improvement in intraoperative care was the introduction of laparoscopy. Laparoscopic surgery for colon and rectal cancer is associated with better short-term outcomes, whereas long-term outcomes regarding survival and recurrence rates are comparable. Nevertheless, long-term results in rectal surgery remain to be seen. Early recognition of anastomotic leakage remains a challenge, though multiple improvements have allowed better management of this complication.

Keywords: Anastomotic leakage; Audits; Colorectal surgery; Enhanced recovery after surgery; Frailty; Laparoscopic surgery; Nutritional status; Sarcopenia.

Publication types

  • Review

MeSH terms

  • Colectomy* / adverse effects
  • Colectomy* / mortality
  • Colectomy* / standards
  • Colorectal Neoplasms / epidemiology
  • Colorectal Neoplasms / mortality
  • Colorectal Neoplasms / pathology
  • Colorectal Neoplasms / surgery*
  • Comorbidity
  • Health Status
  • Humans
  • Laparoscopy* / adverse effects
  • Laparoscopy* / mortality
  • Laparoscopy* / standards
  • Perioperative Care
  • Postoperative Complications / prevention & control
  • Quality Improvement* / standards
  • Quality Indicators, Health Care* / standards
  • Risk Factors
  • Time Factors
  • Treatment Outcome