Intake of energy-dense foods, fast foods, sugary drinks, and breast cancer risk in African American and European American women

Nutr Cancer. 2014;66(7):1187-99. doi: 10.1080/01635581.2014.951737. Epub 2014 Sep 29.

Abstract

Limiting energy-dense foods, fast foods, and sugary drinks that promote weight gain is a cancer prevention recommendation, but no studies have evaluated intake in relation to breast cancer risk in African American (AA) women. In a case-control study with 1692 AA women (803 cases and 889 controls) and 1456 European American (EA) women (755 cases and 701 controls), odds ratios (OR) and 95% confidence intervals (CI) for risk were computed, stratifying for menopausal and estrogen receptor (ER) status. Among postmenopausal EA women, breast cancer risk was associated with frequent consumption of energy-dense foods (OR = 2.95; 95% CI: 1.66-5.22), fast foods (OR = 2.35; 95% CI: 1.38-4.00), and sugary drinks (OR = 2.05; 95% CI: 1.13-3.70). Elevated risk of ER+ tumors in EA women was associated with energy-dense (OR = 1.75; 95% CI: 1.14-2.69) and fast foods (OR = 1.84; 95% CI: 1.22-2.77). Among AA women, frequent fast food consumption was related to premenopausal breast cancer risk (OR = 1.97; 95% CI: 1.13-3.43), and with ER+ tumors. Energy adjustment attenuated risk estimates in AA women, while strengthening them among EA women. Frequent consumption of energy-dense and fast foods that have poor nutritive value appeared to increase breast cancer risk in AA and EA women, with differences by menopausal status and ER status.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • African Americans
  • Aged
  • Beverages / adverse effects*
  • Body Mass Index
  • Breast Neoplasms / epidemiology*
  • Case-Control Studies
  • Diet
  • Dietary Carbohydrates / adverse effects*
  • Energy Intake*
  • European Continental Ancestry Group
  • Fast Foods / adverse effects*
  • Female
  • Humans
  • Logistic Models
  • Middle Aged
  • Nutritive Sweeteners / adverse effects
  • Postmenopause
  • Risk Factors
  • Surveys and Questionnaires
  • Weight Gain
  • Young Adult

Substances

  • Dietary Carbohydrates
  • Nutritive Sweeteners