Inherited hypercoagulable states in children

Am J Pediatr Hematol Oncol. Summer 1989;11(2):170-3.

Abstract

Disorders that predispose children to venous thrombosis include inherited abnormalities of antithrombin III, protein S, protein C, fibrinogen, and plasminogen. Arterial thrombosis may result from disorders that produce endothelial damage, abnormal vascular flow, or increased platelet aggregation. We present here a case of a child who had recurrent thromboses and discuss the evaluation and management of such patients.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antithrombin III Deficiency*
  • Blood Coagulation Disorders / blood*
  • Blood Coagulation Disorders / genetics
  • Cerebral Infarction / blood
  • Cerebral Infarction / genetics
  • Child
  • Family Health
  • Female
  • Glycoproteins / deficiency
  • Humans
  • Male
  • Pedigree
  • Protein C Deficiency
  • Protein S
  • Pulmonary Embolism / blood
  • Pulmonary Embolism / genetics
  • Recurrence
  • Thrombophlebitis / blood
  • Thrombophlebitis / genetics

Substances

  • Glycoproteins
  • Protein S