Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Sep 25;36:e2014019.
doi: 10.4178/epih/e2014019. eCollection 2014.


Free PMC article


Jong-Myon Bae. Epidemiol Health. .
Free PMC article


The concept of meta-epidemiology has been introduced with considering the methodological limitations of systematic review for intervention trials. The paradigm of meta-epidemiology has shifted from a statistical method into a new methodology to close gaps between evidence and practice. Main interest of meta-epidemiology is to control potential biases in previous quantitative systematic reviews and draw appropriate evidences for establishing evidence-base guidelines. Nowadays, the network meta-epidemiology was suggested in order to overcome some limitations of meta-epidemiology. To activate meta-epidemiologic studies, implementation of tools for risk of bias and reporting guidelines such as the Consolidated Standards for Reporting Trials (CONSORT) should be done.

Keywords: Bias; Epidemiology; Meta-analysis as topic; Review literature as topic.

Conflict of interest statement

The author has no conflicts of interest to declare for this study.

Similar articles

See all similar articles

Cited by 2 articles


    1. Bae JM, Park BJ, Ahn YO. Perspectives of clinical epidemiology in Korea. J Korean Med Assoc. 2013;56:718–723. (Korean)
    1. Ioannidis JP, Schmid CH, Lau J. Meta-analysis in hematology and oncology. Hematol Oncol Clin North Am. 2000;14:973–991. - PubMed
    1. Ahn HS, Kim HJ. An introduction to systematic review. J Korean Med Assoc. 2014;57:49–59. (Korean)
    1. Khoshdel A, Attia J, Carney SL. Basic concepts in meta-analysis: A primer for clinicians. Int J Clin Pract. 2006;60:1287–1294. - PubMed
    1. Noble JH., Jr Meta-analysis: Methods, strengths, weaknesses, and political uses. J Lab Clin Med. 2006;147:7–20. - PubMed