Development and validation of an electronic medical record-based disease activity index for Behçet's disease

Clin Exp Rheumatol. 2014 Jul-Aug;32(4 Suppl 84):S40-4. Epub 2014 Sep 30.

Abstract

Objectives: The disease activity of Behçet's disease is inadequately defined, and there is no consensus on how it should be measured. The aim of this study was to verify the usefulness of a simplified electronic medical record (EMR)-based activity index (EMRAI) for Behçet's disease.

Methods: A total of 73 Korean patients with Behçet's disease participated in this study. Two dermatologists interviewed each participant independently using two activity scoring systems: the EMRAI and the Behçet's Disease Current Activity Form (BDCAF). Overall agreement between raters, correlation between activity scoring indices, and total interview run-time were evaluated.

Results: The EMRAI significantly correlated with the BDCAF (Spearman's correlation coefficient, r=0.835), physician-assessed overall activity score (r=0.782), erythrocyte sedimentation rate (r=0.520) and C-reactive protein level (r=0.422). The weighted kappa score for inter-rater agreement of EMRAI showed very good reliability compared with that of BDCAF (0.894 and 0.693, respectively). The mean total run-time for the EMRAI was shorter than that required to administer the BDCAF (95 s and 115 s, respectively).

Conclusions: The EMRAI, an EMR-based simplified activity index of Behçet's disease, facilitates rapid and simple gathering of disease activity data and clinical information.

Publication types

  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Adult
  • Asian People
  • Behcet Syndrome / immunology*
  • Behcet Syndrome / physiopathology*
  • Blood Sedimentation
  • C-Reactive Protein / metabolism
  • Databases, Factual / standards*
  • Databases, Factual / statistics & numerical data
  • Electronic Health Records / organization & administration
  • Electronic Health Records / standards*
  • Electronic Health Records / statistics & numerical data
  • Female
  • Humans
  • Male
  • Middle Aged
  • Observer Variation
  • Prospective Studies
  • Reproducibility of Results
  • Severity of Illness Index*

Substances

  • C-Reactive Protein