Comparative study of Poincaré plot analysis using short electroencephalogram signals during anaesthesia with spectral edge frequency 95 and bispectral index

Anaesthesia. 2015 Mar;70(3):310-7. doi: 10.1111/anae.12885. Epub 2014 Oct 1.

Abstract

The return or Poincaré plot is a non-linear analytical approach in a two-dimensional plane, where a timed signal is plotted against itself after a time delay. Its scatter pattern reflects the randomness and variability in the signals. Quantification of a Poincaré plot of the electroencephalogram has potential to determine anaesthesia depth. We quantified the degree of dispersion (i.e. standard deviation, SD) along the diagonal line of the electroencephalogram-Poincaré plot (named as SD1/SD2), and compared SD1/SD2 values with spectral edge frequency 95 (SEF95) and bispectral index values. The regression analysis showed a tight linear regression equation with a coefficient of determination (R(2) ) value of 0.904 (p < 0.0001) between the Poincaré index (SD1/SD2) and SEF95, and a moderate linear regression equation between SD1/SD2 and bispectral index (R(2) = 0.346, p < 0.0001). Quantification of the Poincaré plot tightly correlates with SEF95, reflecting anaesthesia-dependent changes in electroencephalogram oscillation.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anesthesia, General / methods*
  • Anesthetics, Inhalation
  • Anesthetics, Intravenous
  • Desflurane
  • Electroencephalography / drug effects
  • Electroencephalography / methods*
  • Electroencephalography / statistics & numerical data*
  • Female
  • Heart Rate / drug effects*
  • Humans
  • Isoflurane / analogs & derivatives
  • Male
  • Methyl Ethers
  • Middle Aged
  • Propofol
  • Regression Analysis
  • Sevoflurane

Substances

  • Anesthetics, Inhalation
  • Anesthetics, Intravenous
  • Methyl Ethers
  • Sevoflurane
  • Desflurane
  • Isoflurane
  • Propofol