Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 20 (4), 475-82

Validation and Diagnostic Usefulness of Gastroesophageal Reflux Disease Questionnaire in a Primary Care Level in Mexico

Affiliations

Validation and Diagnostic Usefulness of Gastroesophageal Reflux Disease Questionnaire in a Primary Care Level in Mexico

Miguel Angel Zavala-Gonzales et al. J Neurogastroenterol Motil.

Abstract

Background/aims: Different non-invasive diagnostics strategies have been used to assess patients with gastroesophageal reflux. Gastroesophageal reflux disease (GERD) questionnaire (GerdQ) is a 6-item, easy to use questionnaire that was developed primarily as a diagnostic tool for GERD in primary care. Our aim was to validate and assess diagnostic utility of GerdQ questionnaire in Mexican patients in the primary care setting.

Methods: The study was performed in 3 phases: (1) a questionnaire translation and comprehension study (n = 20), (2) are a reproduci-bility and validation study (50 patients and 50 controls) and (3) a study to assess the clinical utility in 252 subjects with GERD symptoms. Diagnostic accuracy was calculated using endoscopy and/or pH-metry as the gold standard.

Results: Internal consistency measured by the Cronbach's α coefficient was 0.81 for patients and 0.90 for healthy controls, with a mixed coefficient of 0.93. Reproducibility for GerdQ was very good and its discriminating validity was 88%. Most of the pa-tients with erosive reflux and non-erosive reflux with abnormal pH-metry had scores > 8, meanwhile most of the patients with functional heartburn and hypersensitive esophagus had < 8. Sensitivity, specificity and positive predictive value of GerdQ com-pared to the gold standard were 72%, 72% and 87%, respectively.

Conclusions: In Mexico, the GerdQ questionnaire Spanish validated version is useful for GERD diagnosis in the primary care setting.(J Neurogastroenterol Motil 2014;20:475-482).

Keywords: Gastroesophageal reflux; Mexico; Questionnaires; Sensitivity and specificity.

Figures

Figure 1.
Figure 1.
Patients’ distribution according to endoscopic findings and ambulatory 24-hour pH-metry. GERD, gastroesophageal reflux disease.
Figure 2.
Figure 2.
Patients’ distribution according to gastroesophageal reflux disease (GERD) phenotype and different gastroesophageal reflux disease questionnaire cut points.

Similar articles

See all similar articles

Cited by 11 PubMed Central articles

See all "Cited by" articles

References

    1. Vakil N, van Zanten SV, Kahrilas P, Dent J, Jones R, Global Consensus Group The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. Am J Gastroenterol. 2006;101:1900–1920. - PubMed
    1. Katz PO, Gerson LB, Vela MF. Guidelines for the diagnosis and management of gastroesophageal reflux disease. Am J Gastroenterol. 2013;108:308–328. - PubMed
    1. Mouli VP, Ahuja V. Questionnaire based gastroesophageal reflux disease (GERD) assessment scales. Indian J Gastroenterol. 2011;30:108–117. - PubMed
    1. Carlsson R, Dent J, Bolling-Sternevald E, et al. The usefulness of a structured questionnaire in the assessment of symptomatic gastroesophageal reflux disease. Scand J Gastroenterol. 1998;33:1023–1029. - PubMed
    1. Bardhan KD, Stanghellini V, Armstrong D, Berghöfer P, Gatz G, Mönnikes H. Evaluation of GERD symptoms during therapy. Part I. Development of the new GERD questionnaire ReQuest TM. Digestion. 2004;69:229–237. - PubMed

LinkOut - more resources

Feedback