Introduction: Improved survival of very low birth weight (VLBW) premature infants requires urgent intensive care, professional nursing and medical care. On the other hand, long hospital stay period imposes emotional and economic burdens on the family and society. Therefore, it is necessary to clarify the most important factors affecting their hospitalization duration to lessen unwanted outcomes of premature birth and to eliminate or relieve the problems.
Methods: In a descriptive-analytical study, 170 low birth weight premature infants were assessed in a regular daily follow-up in Alzahra Hospital, Tabriz, Iran. Probable factors affecting NICU (neonatal intensive care unit) stay, such as birth age and weight, time of trophic feeding initiation, time of regain birth weight, and duration of parenteral nutrition, were evaluated. Data was analyzed using descriptive statistics and linier regression model in SPSS14. Statistical significance was considered at 0.05.
Results: Mean birth weight and age of infants were 1310.26 ± 804.26 g and 30.51 ± 0.34 weeks, respectively. Duration of NICU stay was 14.51 ± 10.12 days. Intrauterine growth retardation, positive C-reactive protein (CRP) and blood culture during hospitalization stay, bloody or bile stained gastric remnants, days to regain birth weight, and total enteral nutrition intolerance were the most important factors affecting NICU stay among the studied infants.
Conclusion: It seems that eliminating risk factors of intrauterine growth retardation during pregnancy, preventing perinatal and nosocomial infections and taking suitable and tolerable feeding strategies will be effective on NICU stay duration in low birth weight premature infants. Therefore, required policies, especially early trophic feeding, are suggested to eliminate the existing difficulties.
Keywords: Neonatal intensive care; Premature infant; Unit stay; Very low birth weight.
[Multicenter study of the nutritional status of premature infants in neonatal intensive care unit in China: report of 974 cases].Zhonghua Er Ke Za Zhi. 2009 Jan;47(1):12-7. Zhonghua Er Ke Za Zhi. 2009. PMID: 19573373 Clinical Trial. Chinese.
Effect of breast milk on hospital costs and length of stay among very low-birth-weight infants in the NICU.Adv Neonatal Care. 2012 Aug;12(4):254-9. doi: 10.1097/ANC.0b013e318260921a. Adv Neonatal Care. 2012. PMID: 22864006
Outcomes of early nutrition support in extremely low-birth-weight infants.Nutr Clin Pract. 2006 Aug;21(4):395-400. doi: 10.1177/0115426506021004395. Nutr Clin Pract. 2006. PMID: 16870808
Early NICU discharge of very low birth weight infants: a critical review and analysis.Semin Neonatol. 2003 Apr;8(2):95-115. doi: 10.1016/S1084-2756(02)00219-1. Semin Neonatol. 2003. PMID: 15001147 Review.
Practice of enteral nutrition in very low birth weight and extremely low birth weight infants.World Rev Nutr Diet. 2014;110:201-14. doi: 10.1159/000358468. Epub 2014 Apr 11. World Rev Nutr Diet. 2014. PMID: 24751631 Review.
Cited by 1 article
The experiences of parents with infants in Neonatal Intensive Care Unit.Iran J Nurs Midwifery Res. 2013 May;18(3):208-13. Iran J Nurs Midwifery Res. 2013. PMID: 23983756 Free PMC article.