A 3D cellular context for the macromolecular world

Nat Struct Mol Biol. 2014 Oct;21(10):841-5. doi: 10.1038/nsmb.2897.


We report the outcomes of the discussion initiated at the workshop entitled A 3D Cellular Context for the Macromolecular World and propose how data from emerging three-dimensional (3D) cellular imaging techniques—such as electron tomography, 3D scanning electron microscopy and soft X-ray tomography—should be archived, curated, validated and disseminated, to enable their interpretation and reuse by the biomedical community.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cells / ultrastructure*
  • Data Curation / methods*
  • Electron Microscope Tomography*
  • Humans
  • Imaging, Three-Dimensional*
  • Macromolecular Substances / ultrastructure*
  • Microscopy, Electron, Scanning
  • Molecular Conformation
  • Tomography, X-Ray*


  • Macromolecular Substances