Effects of laser vs ultrasound on bone healing after distraction osteogenesis: A histomorphometric analysis

Angle Orthod. 2015 Jul;85(4):555-61. doi: 10.2319/061414-431.1. Epub 2014 Oct 7.

Abstract

Objective: To assess the effects of low-level laser irradiation vs ultrasound irradiation on bone healing after distraction osteogenesis.

Materials and methods: Distraction osteogenesis was performed with rapid maxillary expansion devices (Hyrax-Morelli, Sorocaba, São Paulo Brazil) in 24 rabbits (Oryctolagus cuniculus). After a 2-day latency period, the distraction devices were activated for 10 days at a rate of 1 mm/d. Four groups of six animals were treated as follows: (1) control, (2) laser irradiation on the right side, (3) ultrasound irradiation on the right side, and (4) laser irradiation on the right side and ultrasound on the left side. Histomorphometric analysis was used to assess the bone healing area. Analysis of variance was used to perform the statistical analyses.

Results: The influence of low-intensity laser associated with ultrasound irradiation on bone healing was statistically significant. The analyses showed the greatest amount of bone healing in the jaws of animals in group 4, which received treatment with both ultrasound and laser.

Conclusion: This study concluded that bone healing is accelerated with the application of laser irradiation. The greatest effects were observed with combined ultrasound and laser treatment.

Keywords: Bone healing; Distraction osteogenesis; Histomorphometry, Laser; Rabbits; Ultrasound.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Bone Marrow / anatomy & histology
  • Bone Matrix / anatomy & histology
  • Bone Regeneration / physiology
  • Cancellous Bone / anatomy & histology
  • Image Processing, Computer-Assisted / methods
  • Low-Level Light Therapy / methods*
  • Male
  • Maxilla / anatomy & histology*
  • Maxilla / radiation effects
  • Maxilla / surgery
  • Microscopy / methods
  • Osteoblasts / cytology
  • Osteocytes / cytology
  • Osteogenesis / physiology
  • Osteogenesis, Distraction / methods*
  • Palatal Expansion Technique / instrumentation
  • Rabbits
  • Time Factors
  • Ultrasonic Therapy / methods*
  • Wound Healing / physiology