Evaluation of targeted mass cholera vaccination strategies in Bangladesh: a demonstration of a new cost-effectiveness calculator

Am J Trop Med Hyg. 2014 Dec;91(6):1181-1189. doi: 10.4269/ajtmh.14-0159. Epub 2014 Oct 6.


Growing interest in mass vaccination with oral cholera vaccine in endemic and epidemic settings will require policymakers to evaluate how to allocate these vaccines in the most efficient manner. Because cholera, when treated properly, has a low case fatality rate, it may not be economically feasible to vaccinate an entire population. Using a new publicly available calculator for estimating the cost-effectiveness of mass vaccination, we show how targeting high-risk subpopulations for vaccination could be cost-effective in Bangladesh. The approach described here is general enough to adapt to different settings or to other vaccine-preventable diseases.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Bangladesh
  • Child
  • Child, Preschool
  • Cholera Vaccines / administration & dosage*
  • Cholera Vaccines / economics
  • Cost-Benefit Analysis*
  • Health Services Accessibility
  • Humans
  • Infant


  • Cholera Vaccines