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Review
. 2014 Sep 23:2:101.
doi: 10.3389/fped.2014.00101. eCollection 2014.

Endocrinopathies in survivors of childhood neoplasia

Nicole Barnes  1 , Wassim Chemaitilly  2
Affiliations
Free PMC article
Review

Endocrinopathies in survivors of childhood neoplasia

Nicole Barnes et al. Front Pediatr. .
Free PMC article

Abstract

Advancements in cancer treatments have increased the number of survivors of childhood cancers. Endocrinopathies are common complications following cancer therapy and may occur decades later. The objective of the current review is to address the main endocrine abnormalities detected in childhood cancer survivors including disorders of the hypothalamic-pituitary axis, thyroid, puberty, gonads, bone, body composition, and glucose metabolism.

Keywords: childhood cancer survivors; endocrinology; gonads; growth; puberty; thyroid disorders.

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Figures

Figure 1
Figure 1
Prevalence of endocrine disorders at the last follow-up visit by gender. Reproduced with permission from Ref. (4) ©2013 European Society of Endocrinology.
Figure 2
Figure 2
Growth hormone secretion after hypothalamic/pituitary exposures to radiotherapy. Reproduced with permission from Ref. (13) ©2011 by American Society of Clinical Oncology.
See this image and copyright information in PMC

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