Rethinking "enterotypes"

Cell Host Microbe. 2014 Oct 8;16(4):433-7. doi: 10.1016/j.chom.2014.09.013.


Classification of the human gut microbiome into distinct types, or "enterotypes," provides an attractive framework for understanding microbial variation in health and disease. However, as discussed here, several different methods of collapsing enterotype variation into a few discrete clusters suggest that enterotype distribution is continuous and can vary widely within an individual.

MeSH terms

  • Bacteria / classification*
  • Bacteria / genetics*
  • Biota*
  • Cluster Analysis
  • Gastrointestinal Tract / microbiology*
  • Genetic Variation
  • Genotype
  • Humans
  • Metagenome*