Carbamazepine-induced tics

Clin Neuropharmacol. 1989 Aug;12(4):298-302. doi: 10.1097/00002826-198908000-00007.


Although a variety of dyskinesias are known to develop during anticonvulsant therapy, carbamazepine-induced tics are rarely recognized. We report three patients with an underlying movement disorder (Huntington's disease, tardive dyskinesia, and Tourette's syndrome) who experienced the onset or exacerbation of tics after the introduction of carbamazepine. These cases confirm the phenomenon of carbamazepine-induced tics and suggest that basal ganglia neuropathology may be an important predisposing factor. The dopaminergic effects of carbamazepine may be responsible for the induction of tics.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Alzheimer Disease / complications
  • Alzheimer Disease / drug therapy
  • Carbamazepine / adverse effects*
  • Dyskinesia, Drug-Induced / complications
  • Dyskinesia, Drug-Induced / drug therapy
  • Female
  • Humans
  • Huntington Disease / complications
  • Huntington Disease / drug therapy
  • Male
  • Tic Disorders / chemically induced*
  • Tic Disorders / physiopathology
  • Tourette Syndrome / complications
  • Tourette Syndrome / drug therapy


  • Carbamazepine