Polyarthritis associated with cutaneous T cell lymphoma

J Rheumatol. 1989 Oct;16(10):1379-82.


This is the first reported synovial biopsy of a patient with concurrent onset of cutaneous T cell lymphoma and polyarthritis. The biopsy revealed a nonspecific chronic inflammatory process. Immunoperoxidase technique using monoclonal antibodies showed a mixture of helper T cells, suppressor T cells and B cells in the synovial infiltrate. Tumor infiltration was not seen. Our findings indicate that the arthritis associated with cutaneous T cell lymphoma is most likely a reactive phenomenon.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Arthritis / etiology*
  • Biopsy
  • Hand
  • Humans
  • Lymphoma / complications*
  • Lymphoma / pathology
  • Male
  • Skin Neoplasms / complications*
  • Skin Neoplasms / pathology
  • Synovial Membrane / pathology
  • T-Lymphocytes
  • T-Lymphocytes, Helper-Inducer / pathology
  • T-Lymphocytes, Regulatory / pathology
  • Wrist Joint