Increased noneosinophilic nasal polyps in chronic rhinosinusitis in US second-generation Asians suggest genetic regulation of eosinophilia

J Allergy Clin Immunol. 2015 Feb;135(2):576-9. doi: 10.1016/j.jaci.2014.08.031. Epub 2014 Oct 11.


In this study we found a significantly lower eosinophilia in nasal polyps surgically removed from second-generation Asian patients, similar to studies of native-born patients in Asian countries, suggesting the hypothesis that there may be genetic regulation of eosinophilia.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Asian Americans / genetics*
  • Chronic Disease
  • Eosinophilia / etiology*
  • Humans
  • Nasal Polyps / complications*
  • Rhinitis / complications*
  • Rhinitis / genetics*
  • Sinusitis / complications*
  • Sinusitis / genetics*
  • United States