Neural circuitry for rat recognition memory

Behav Brain Res. 2015 May 15:285:131-9. doi: 10.1016/j.bbr.2014.09.050. Epub 2014 Oct 12.


Information concerning the roles of different brain regions in recognition memory processes is reviewed. The review concentrates on findings from spontaneous recognition memory tasks performed by rats, including memory for single objects, locations, object-location associations and temporal order. Particular emphasis is given to the potential roles of different regions in the circuit of interacting structures involving the perirhinal cortex, hippocampus, medial prefrontal cortex and medial dorsal thalamus in recognition memory for the association of objects and places. It is concluded that while all structures in this circuit play roles critical to such memory, these roles can potentially be differentiated and differences in the underlying synaptic and biochemical processes involved in each region are beginning to be uncovered.

Keywords: Hippocampus; Medial prefrontal cortex; Neural circuit; Object recognition memory; Perirhinal cortex.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Brain / physiology*
  • Neural Pathways / physiology
  • Rats
  • Recognition, Psychology / physiology*