[Predictors of exercise capacity improvement in patients after an acute coronary event during inpatient rehabilitation]

Rehabilitation (Stuttg). 2014 Oct;53(5):341-5. doi: 10.1055/s-0034-1370983. Epub 2014 Oct 15.
[Article in German]


Objective Patients who suffered from an acute coronary syndrome (ACS) boast a low exercise capacity (EC). To enhance EC is a core component of cardiac rehabilitation (CR). The aim of the study was to investigate predictors of exercise capacity to optimize the rehabilitation process in untrained subgroups.

Method: 47 286 patients (mean age 64±11.62, 74.5% male) were enclosed in the TROL registry. All patients underwent a bicycle stress test at admission and discharge. The dependent variable for the univariate analysis and multivariate logistic regression was the increase of EC during CR, with a cutoff of 15 Watts (pre/post design). Furthermore comorbidities and physical activity before the index event were analyzed.

Results: Exercise capacity enhancement differs between active and inactive patients significantly (21.84 Watt vs. 16.35 Watt; p<0.001). While a male gender (OR 1.62 [95% CI: 1.51-1.74]) and physical activity before rehabilitation (OR 1.85 [95% CI: 1.75-1.97]) were positive, comorbidities and age (OR 0.82 [95% CI: 0.74-0.90]) were negative predictors.

Conclusion: In cardiac rehabilitation settings special exercise training programs for elderly and comorbid patients are needed, to enhance their exercise capacity sufficiently.

Publication types

  • Controlled Clinical Trial
  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Coronary Syndrome / epidemiology
  • Acute Coronary Syndrome / physiopathology*
  • Acute Coronary Syndrome / rehabilitation*
  • Age Distribution
  • Exercise Test / statistics & numerical data
  • Exercise Tolerance*
  • Female
  • Germany / epidemiology
  • Hospitalization / statistics & numerical data*
  • Humans
  • Male
  • Middle Aged
  • Physical Fitness*
  • Prevalence
  • Prognosis
  • Registries*
  • Risk Assessment
  • Sex Distribution
  • Treatment Outcome