Cesarean section plus delayed cord clamping approach in the perinatal management of congenital high airway obstruction syndrome (CHAOS): a case report

J Neonatal Perinatal Med. 2014 Jan 1;7(3):237-9. doi: 10.3233/NPM-14814006.


In this case, we describe a newborn with prenatal diagnosis of congenital high airway obstruction syndrome (CHAOS), successfully managed with a cesarean section with delayed cord clamping 180 seconds. In case of prenatal diagnosis of CHAOS, prompt airway intervention at delivery allows survival of this otherwise fatal condition. Ex utero intrapartum treatment (EXIT) is considered the elective procedure to secure the fetal airway before the baby is completely separated from the maternal circulation. In cases where the EXIT procedure is not possible for maternal reasons (Ballantyne's syndrome), delayed cord clamping may serve as an alternative method to manage CHAOS.

Keywords: CHAOS; EXIT; delayed cord clamping.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Airway Obstruction / congenital
  • Airway Obstruction / diagnosis
  • Airway Obstruction / therapy*
  • Cesarean Section*
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Infant, Premature, Diseases / diagnosis
  • Infant, Premature, Diseases / therapy*
  • Perinatal Care / methods*
  • Pregnancy
  • Prenatal Diagnosis
  • Resuscitation / methods
  • Syndrome
  • Umbilical Cord