Dynamic bias and its implications for GPCR drug discovery

Nat Rev Drug Discov. 2014 Nov;13(11):869. doi: 10.1038/nrd3954-c3. Epub 2014 Oct 17.

Authors

Martin C Michel¹, Roland Seifert², Richard A Bond³

Affiliations

¹ Department of Pharmacology, Johannes Gutenberg University, Obere Zahlbacher Strasse 67, 51101 Mainz, Germany.
² Department of Pharmacology, Hannover Medical School, Carl-Neuberg-Strasse 1, D-30625 Hannover, Germany.
³ Department of Pharmacology and Pharmaceutical Sciences, Science and Research Building 2, Room 521, University of Houston, Houston, Texas 77204-5037, USA.

PMID: 25323926
DOI: 10.1038/nrd3954-c3

No abstract available

Publication types

Letter
Comment

MeSH terms

Animals
Drug Discovery*
Humans
Signal Transduction / physiology*