How to make more published research true

PLoS Med. 2014 Oct 21;11(10):e1001747. doi: 10.1371/journal.pmed.1001747. eCollection 2014 Oct.


In a 2005 paper that has been accessed more than a million times, John Ioannidis explained why most published research findings were false. Here he revisits the topic, this time to address how to improve matters. Please see later in the article for the Editors' Summary.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Publications / standards*
  • Publishing / standards*
  • Research

Grants and funding

The Meta-Research Innovation Center at Stanford is funded by the Laura and John Arnold Foundation. The funders had no role in the decision to publish or in the preparation of the manuscript.