The Canadian kidney paired donation program: a national program to increase living donor transplantation

Transplantation. 2015 May;99(5):985-90. doi: 10.1097/TP.0000000000000455.


Background: Establishment of a national kidney paired donation (KPD) program represents a unique achievement in Canada's provincially organized health care system.

Methods: Key factors enabling program implementation included consultation with international experts, formation of a unique organization with a mandate to facilitate interprovincial collaboration, and the volunteer efforts of members of the Canadian transplant community to overcome a variety of logistical barriers.

Results: As of December 2013, the program had facilitated 240 transplantations including 10% with Calculated panel reactive antibody (cPRA) ≥97%. Unique features of the Canadian KPD program include participation of n = 55 nondirected donors, performance of only donor specific antibody negative transplants, the requirement for donor travel, and nonuse of bridge donors.

Conclusion: The national KPD program has helped maintain the volume of living kidney donor transplants in Canada over the past 5 years and serves as a model of inter-provincial collaboration to improve the delivery of health care to Canadians.

MeSH terms

  • ABO Blood-Group System / immunology
  • Blood Group Incompatibility
  • Canada
  • Histocompatibility Testing
  • Humans
  • Kidney Transplantation*
  • Living Donors*
  • National Health Programs


  • ABO Blood-Group System