Screening for novel plant sources of prenyloxyanthraquinones: Senna alexandrina Mill. and Aloe vera (L.) Burm. F

Nat Prod Res. 2015;29(2):180-4. doi: 10.1080/14786419.2014.971792. Epub 2014 Oct 24.


As a continuation of our ongoing studies aimed to reveal the presence of oxyprenylated anthraquinones in plants claimed to have a laxative effect, in this article, we describe the extraction and HPLC separation of madagascin (3-isopentenyloxyemodin) and 3-geranyloxyemodine from dried leaves and fruits of Senna alexandrina Mill. (Leguminosae) and leaves and gel of Aloe vera (L.) Burm. F. (Xanthorrhoeaceae). Both compounds are described herein for the first time as components of extracts of the title plants.

Keywords: 3-geranyloxyemodin; Aloe vera; Senna alexandrina; anthraquinones; madagascin; oxyprenylated secondary metabolites; polyketides.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aloe / chemistry*
  • Anthraquinones / chemistry*
  • Anthraquinones / isolation & purification
  • Chromatography, High Pressure Liquid
  • Fruit / chemistry
  • Hemiterpenes / chemistry*
  • Hemiterpenes / isolation & purification
  • Molecular Structure
  • Plant Extracts / chemistry
  • Plant Leaves / chemistry
  • Senna Plant / chemistry*


  • 3-geranyloxyemodine
  • 3-isopentenyloxyemodin
  • Anthraquinones
  • Hemiterpenes
  • Plant Extracts