Intravitreal polypoidal choroidal vasculopathy in radiation retinopathy

Ophthalmic Surg Lasers Imaging Retina. Nov-Dec 2014;45(6):585-8. doi: 10.3928/23258160-20141008-04. Epub 2014 Oct 29.

Abstract

A 30-year-old woman diagnosed with choroidal melanoma and treated with plaque radiation and transpupillary thermotherapy 5 years earlier presented with recalcitrant proliferative radiation retinopathy despite multiple intravitreal anti-vascular endothelial growth factor injections. Swept-source and spectral-domain optical coherence tomography (OCT) demonstrated intravitreal polyps lying on the surface of atrophied chorioretinal tissue. Fluorescein angiography (FA) revealed leakage from these saccular choroidal neovasculopathic vessels adjacent to a large zone of poor choroidal perfusion. Intravitreal polypoidal choroidal vasculopathy may be associated with radiation retinopathy and is well-demonstrated with swept-source and spectral-domain OCT and FA.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Brachytherapy
  • Capillary Permeability
  • Choroid Neoplasms / radiotherapy
  • Choroidal Neovascularization / diagnosis
  • Choroidal Neovascularization / etiology*
  • Female
  • Fluorescein Angiography
  • Humans
  • Hyperthermia, Induced
  • Iodine Radioisotopes / adverse effects*
  • Melanoma / radiotherapy
  • Polyps / diagnosis
  • Polyps / etiology*
  • Radiation Injuries / diagnosis
  • Radiation Injuries / etiology*
  • Retina / pathology
  • Retina / radiation effects*
  • Retinal Diseases / diagnosis
  • Retinal Diseases / etiology*
  • Tomography, Optical Coherence
  • Vitreous Body / pathology

Substances

  • Iodine Radioisotopes