Navigating protected genomics data with UCSC Genome Browser in a Box

Bioinformatics. 2015 Mar 1;31(5):764-6. doi: 10.1093/bioinformatics/btu712. Epub 2014 Oct 27.


Genome Browser in a Box (GBiB) is a small virtual machine version of the popular University of California Santa Cruz (UCSC) Genome Browser that can be run on a researcher's own computer. Once GBiB is installed, a standard web browser is used to access the virtual server and add personal data files from the local hard disk. Annotation data are loaded on demand through the Internet from UCSC or can be downloaded to the local computer for faster access.

Availability and implementation: Software downloads and installation instructions are freely available for non-commercial use at GBiB requires the installation of open-source software VirtualBox, available for all major operating systems, and the UCSC Genome Browser, which is open source and free for non-commercial use. Commercial use of GBiB and the Genome Browser requires a license (

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computational Biology
  • Databases, Genetic*
  • Genome, Human*
  • Genomics / methods*
  • Humans
  • Information Storage and Retrieval*
  • Internet
  • Sequence Analysis, DNA / methods*
  • Software
  • Universities
  • User-Computer Interface