Contaminated handwashing sinks as the source of a clonal outbreak of KPC-2-producing Klebsiella oxytoca on a hematology ward

Antimicrob Agents Chemother. 2015 Jan;59(1):714-6. doi: 10.1128/AAC.04306-14. Epub 2014 Oct 27.

Abstract

We investigated sinks as possible sources of a prolonged Klebsiella pneumonia carbapenemase (KPC)-producing Klebsiella oxytoca outbreak. Seven carbapenem-resistant K. oxytoca isolates were identified in sink drains in 4 patient rooms and in the medication room. Investigations for resistance genes and genetic relatedness of patient and environmental isolates revealed that all the isolates harbored the blaKPC-2 and blaTEM-1 genes and were genetically indistinguishable. We describe here a clonal outbreak caused by KPC-2-producing K. oxytoca, and handwashing sinks were a possible reservoir.

MeSH terms

  • Cross Infection / epidemiology
  • Cross Infection / etiology*
  • Cross Infection / microbiology
  • Disease Outbreaks
  • Equipment Contamination*
  • Hand Disinfection
  • Hematology
  • Hospital Departments
  • Humans
  • Klebsiella Infections / epidemiology
  • Klebsiella Infections / etiology*
  • Klebsiella Infections / microbiology
  • Klebsiella oxytoca* / enzymology
  • beta-Lactamases

Substances

  • beta-lactamase KPC-2
  • beta-Lactamases