Abstract
Two novel G3P[4] rotavirus strains were detected from children with acute diarrhea in Sendai, Japan, identified as a G3-P[4]-I2-R2-C2-M2-A2-N2-T2-E2-H2 genotype constellation by whole-genome sequence analysis. The VP7 gene of the two strains displayed the highest nucleotide sequence identity (91 %) and showed a close genetic relationship (99 % bootstrap value) to an equine rotavirus reported in India. The other gene segments were related to human group A rotaviruses. This report suggests a possible reassortment event between human and equine rotaviruses.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antigens, Viral / genetics
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Capsid Proteins / genetics
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Child, Preschool
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Cluster Analysis
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Diarrhea / epidemiology
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Diarrhea / virology
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Female
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Horses
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Humans
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Infant
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Japan / epidemiology
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Male
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Molecular Sequence Data
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Phylogeny
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RNA, Viral / genetics*
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Reassortant Viruses / genetics*
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Reassortant Viruses / isolation & purification*
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Rotavirus / genetics*
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Rotavirus / isolation & purification*
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Rotavirus Infections / epidemiology
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Rotavirus Infections / virology*
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Sequence Analysis, DNA
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Sequence Homology, Amino Acid
Substances
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Antigens, Viral
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Capsid Proteins
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RNA, Viral
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VP7 protein, Rotavirus
Associated data
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GENBANK/KJ639012
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GENBANK/KJ639013
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GENBANK/KJ639014
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GENBANK/KJ639015
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GENBANK/KJ639016
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GENBANK/KJ639017
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GENBANK/KJ639018
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GENBANK/KJ639019
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GENBANK/KJ639020
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GENBANK/KJ639021
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GENBANK/KJ639022
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GENBANK/KJ639023
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GENBANK/KJ639024
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GENBANK/KJ639025
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GENBANK/KJ639026
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GENBANK/KJ639027
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GENBANK/KJ639028
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GENBANK/KJ639029
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GENBANK/KJ639030
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GENBANK/KJ639031
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GENBANK/KJ639032
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GENBANK/KJ639033