Varicella-zoster virus infections in pregnancy

Am Fam Physician. 1989 Feb;39(2):89-98.


Varicella-zoster virus can cause a distinct congenital syndrome, a potentially fatal neonatal infection and life-threatening maternal illness. Physicians can reduce morbidity from these conditions by advising nonimmune pregnant women to avoid exposure to chickenpox and herpes zoster and, when indicated, by promptly administering varicella-zoster immune globulin. When prevention fails, acyclovir may be effective therapy.

Publication types

  • Review

MeSH terms

  • Abnormalities, Multiple / etiology
  • Chickenpox* / congenital
  • Chickenpox* / therapy
  • Female
  • Fetal Diseases
  • Herpes Zoster* / therapy
  • Herpesvirus 3, Human / immunology
  • Humans
  • Immune Sera
  • Immunization, Passive
  • Pregnancy
  • Pregnancy Complications, Infectious* / therapy
  • Pregnancy Outcome
  • Syndrome


  • Immune Sera
  • varicella-zoster immune globulin