Use of PER977 to reverse the anticoagulant effect of edoxaban

N Engl J Med. 2014 Nov 27;371(22):2141-2. doi: 10.1056/NEJMc1411800. Epub 2014 Nov 5.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arginine / analogs & derivatives*
  • Arginine / pharmacokinetics
  • Arginine / pharmacology
  • Blood Coagulation / drug effects*
  • Factor Xa Inhibitors*
  • Heparin Antagonists / pharmacokinetics
  • Heparin Antagonists / pharmacology*
  • Humans
  • Piperazines / pharmacokinetics
  • Piperazines / pharmacology*
  • Pyridines / antagonists & inhibitors*
  • Thiazoles / antagonists & inhibitors*

Substances

  • Factor Xa Inhibitors
  • Heparin Antagonists
  • PER977
  • Piperazines
  • Pyridines
  • Thiazoles
  • Arginine
  • edoxaban

Associated data

  • ClinicalTrials.gov/NCT01826266