Potential use of in vivo proton spectroscopy for head and neck lesions

Radiol Clin North Am. 1989 Mar;27(2):243-54.


Early experience with in vivo MRS has shown its potential for obtaining biochemical information, thus enhancing the diagnostic sensitivity of MRI studies. Further work on combined MRI and in vivo MRS is needed, with the goal of characterization and abnormal conditions according to their spectral patterns and for identification of tumor markers. We presented in this communication our preliminary results. It seems that the resonance from melanin can be used as a marker for melanotic tumors.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biomarkers, Tumor / analysis
  • Head and Neck Neoplasms / analysis
  • Head and Neck Neoplasms / diagnosis*
  • Head and Neck Neoplasms / metabolism
  • Humans
  • Magnetic Resonance Imaging
  • Magnetic Resonance Spectroscopy / methods*
  • Melanins / analysis
  • Protons*


  • Biomarkers, Tumor
  • Melanins
  • Protons