Maintaining neural stem cell identity in the brain

Elife. 2014 Nov 6;3:e05000. doi: 10.7554/eLife.05000.


In the developing fruit fly brain, a protein called Trithorax increases the number of neural cells produced from a single stem cell, in part by regulating the transcription of the target genes buttonhead and pointed.

Keywords: D. melanogaster; buttonhead; developmental biology; intermediate neural progenitor; neural stem cells; neuroblast; pointed; stem cells; trithorax.

MeSH terms

  • Animals
  • Brain / cytology*
  • Cell Lineage
  • Drosophila Proteins / metabolism
  • Drosophila melanogaster / cytology*
  • Drosophila melanogaster / metabolism
  • Neural Stem Cells / cytology*


  • Drosophila Proteins