Cytotoxicity of doxycycline effluent generated by the Fenton process

ScientificWorldJournal. 2014;2014:439461. doi: 10.1155/2014/439461. Epub 2014 Oct 14.

Abstract

This study aims at determining the Minimum Inhibitory Concentration with Escherichia coli ATCC 25922 and cytotoxicity to L929 cells (ATCC CCL-1) of the waste generated by doxycycline degradation by the Fenton process. This process has shown promise in this treatment thanks mainly to the fact that the waste did not show any relevant inhibitory effect on the test organism and no cytotoxicity to L-929 cells, thus demonstrating that the antibiotic properties were inactivated.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Bacterial Agents / chemistry*
  • Anti-Bacterial Agents / toxicity
  • Cell Line
  • Cell Survival / drug effects
  • Doxycycline / chemistry*
  • Doxycycline / toxicity
  • Escherichia coli / drug effects
  • Escherichia coli / growth & development
  • Fibroblasts / drug effects
  • Humans
  • Hydrogen Peroxide / chemistry*
  • Iron / chemistry*
  • Mice
  • Microbial Sensitivity Tests
  • Waste Disposal, Fluid
  • Water Pollutants, Chemical / chemistry*
  • Water Pollutants, Chemical / toxicity

Substances

  • Anti-Bacterial Agents
  • Fenton's reagent
  • Water Pollutants, Chemical
  • Hydrogen Peroxide
  • Iron
  • Doxycycline