An expedient approach to synthesize fluorescent 3-substituted 4H-quinolizin-4-ones via (η(4)-vinylketene)-Fe(CO)3 complexes

Dalton Trans. 2015 Jan 14;44(2):578-90. doi: 10.1039/c4dt03021d.


An efficient and practical methodology for the synthesis of 3-substituted 4H-quinolizin-4-ones using (η(4)-vinylketene)-Fe(CO)3 complexes as key intermediates has been developed. The advantage of this transformation lies in the use of simple and readily available starting materials and mild carbonylation conditions. The fluorescent properties of these compounds were determined and the quantum yield was obtained, ranging from 0.04 to 0.36 depending on the substituent.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbonates / chemistry*
  • Crystallography, X-Ray
  • Ethylenes / chemistry*
  • Fluorescent Dyes / chemistry*
  • Iron / chemistry*
  • Ketones / chemistry*
  • Magnetic Resonance Spectroscopy
  • Models, Molecular
  • Quinolizines / chemistry*
  • Spectrometry, Mass, Fast Atom Bombardment
  • Spectrophotometry, Ultraviolet
  • Spectroscopy, Fourier Transform Infrared


  • Carbonates
  • Ethylenes
  • Fluorescent Dyes
  • Ketones
  • Quinolizines
  • Iron
  • ketene