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Case Reports
. 2011 Sep 28;3(2):e27.
doi: 10.4081/dr.2011.e27. eCollection 2011 Aug 3.

Lichen Sclerosus Et Atrophicans, Scleroderma en Coup De Sabre and Lyme Borreliosis

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Free PMC article
Case Reports

Lichen Sclerosus Et Atrophicans, Scleroderma en Coup De Sabre and Lyme Borreliosis

Nicoletta Gubertini et al. Dermatol Reports. .
Free PMC article

Abstract

Lichen sclerosus et atrophicans (LSA) is a chronic, inflammatory skin disease of unknown etiology, characterized by atrophy. We report a case of LSA with frontoparietal distribution, mimicking scleroderma en coup de sabre, causing scarring alopecia. The case was associated with Borrelia infection. The lesion improved with 2 cycles of antibiotic therapy with ceftriaxone 2 gr/day i.v for 21 days associated with UVA-1 therapy and local and systemic vitamin E supply (400 mg 2x/day per os for 3 months). This case stresses the importance of identifying clinical manifestations associated with Lyme disease and the use of tissue PCR to detect borrelial DNA in patients with these lesions, but characterized by negative serology for Borrelia.

Keywords: Borrelia.; Lyme borreliosis; PCR; frontoparietal distribution; lichen sclerosus et atrophicans.

Figures

Figure 1
Figure 1
Lichen sclerosus et atrophicans with frontoparietal distribution, mimicking scleroderma en coup de sabre.
Figure 2
Figure 2
H&E stained section of the lesion (A) 2,5 × magnification of the entire histological section, (B) 20× magnification of the lichen sclerosus et atrophicans features (C) 40× magnification of the lymphatic infiltrate.

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