A clinical trial to investigate the effect of Cynatine HNS on hair and nail parameters

ScientificWorldJournal. 2014;2014:641723. doi: 10.1155/2014/641723. Epub 2014 Oct 16.


Objective: A new, novel product, Cynatine HNS, was evaluated for its effects as a supplement for improving various aspects of hair and nails in a randomized, double-blind, placebo-controlled clinical trial.

Methods: A total of 50 females were included and randomized into two groups. The active group (n = 25) received 2 capsules containing Cynatine HNS, comprised of Cynatine brand keratin (500 mg) plus vitamins and minerals, per day, and the placebo group (n = 25) received 2 identical capsules of maltodextrin per day for 90 days. End points for hair loss, hair growth, hair strength, amino acid composition, and hair luster were measured. End points were also measured for nail strength and the appearance of nails.

Results: The results show that subjects taking Cynatine HNS showed statistically significant improvements in their hair and nails when compared to placebo.

Conclusion: Cynatine HNS is an effective supplement for improving hair and nails in 90 days or less. EudraCT number is 2014-002645-22.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Dietary Supplements
  • Double-Blind Method
  • Female
  • Hair / chemistry*
  • Hair / drug effects*
  • Hair / pathology
  • Humans
  • Keratins / administration & dosage*
  • Keratins / chemistry
  • Keratins / metabolism
  • Middle Aged
  • Minerals / administration & dosage
  • Nails / chemistry*
  • Nails / drug effects*
  • Nails / pathology
  • Vitamins / administration & dosage


  • Minerals
  • Vitamins
  • Keratins