Purpose: To describe a case of bilateral choroidal masses leading to the diagnosis of Rosai-Dorfman disease.
Method: Case report. Color photographs, fluorescein angiography, autofluorescence, indocyanine green angiography, and high-definition optical coherence tomography imaging of both eyes and computed tomography and biopsy of pelvis mass were performed. A 47-year-lady presented with unknown choroidal masses in both eyes. She had no visual complaints. Her medical history was noncontributory.
Results: Workup included a computed tomography of the chest and abdomen that demonstrated soft tissue masses in the renal pelvis bilaterally. A core needle biopsy from the renal mass demonstrated numerous histiocytoid that were positive for CD163 and S100 protein.
Conclusion: Based on this spectrum of findings, the diagnosis of Rosai-Dorfman disease was made. To date, the patient has been followed-up for 3 years without medical intervention and without visual deterioration. Careful follow-up is a reasonable management if patients are asymptomatic.
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Cited by 2 articles
Choroidal involvement in Rosai-Dorfman syndrome may be depicted and followed using enhanced depth imaging optical coherence tomography (EDI-OCT).Graefes Arch Clin Exp Ophthalmol. 2015 Oct;253(10):1821-2. doi: 10.1007/s00417-015-2988-0. Epub 2015 Apr 1. Graefes Arch Clin Exp Ophthalmol. 2015. PMID: 25825230 No abstract available.
Choroidal involvement in Rosai-Dorfman syndrome may be depicted and followed using enhanced depth imaging optical coherence tomography (EDI-OCT).Graefes Arch Clin Exp Ophthalmol. 2015 Oct;253(10):1819-20. doi: 10.1007/s00417-015-2987-1. Epub 2015 Mar 20. Graefes Arch Clin Exp Ophthalmol. 2015. PMID: 25791357 No abstract available.