Retinal pigment epithelium tear in vogt-koyanagi-harada disease

Retin Cases Brief Rep. Fall 2011;5(4):284-6. doi: 10.1097/ICB.0b013e3181f66d11.


Purpose: The purpose of this study was to report a case of Vogt-Koyanagi-Harada disease causing large tears of the retinal pigment epithelium (RPE).

Methods: Case report and literature review.

Results: A 41-year-old woman presented with headache, tinnitus, and bilateral panuveitis with multiple serous retinal detachments. She was started on oral prednisone, and the inflammation and serous detachments subsided. However, 2 weeks later, she developed large RPE tears.

Conclusion: Vogt-Koyanagi-Harada disease is an inflammatory disorder of the choroid; however, irregularities in the RPE have been noted, most recently with the use of spectral domain ophthalmic coherence tomography. The finding of RPE tear with resolution of serous retinal detachment may further implicate involvement of the RPE in the disease process.