Invasive Saccharomyces cerevisiae infection: a friend turning foe?

Saudi J Kidney Dis Transpl. 2014 Nov;25(6):1266-9. doi: 10.4103/1319-2442.144265.

Abstract

We report a very rare case of acute pyelonephritis in a 51-year-old female with a history of chronic kidney disease (CKD) and diabetes caused by a normally benign and a well-known human commensal organism, Saccharomyces cerevisiae that is very often prescribed as a probiotic in modern medical practice. The causal role of S. cerevisiae was confirmed by its isolation in blood, urine, stool as well as vaginal swabs thus proving its virulent nature in suitable situations.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Antifungal Agents / therapeutic use
  • Feces / microbiology
  • Female
  • Fungemia / diagnosis
  • Fungemia / drug therapy
  • Fungemia / microbiology
  • Humans
  • Middle Aged
  • Mycoses / blood
  • Mycoses / diagnosis
  • Mycoses / drug therapy
  • Mycoses / microbiology*
  • Mycoses / urine
  • Pyelonephritis / blood
  • Pyelonephritis / diagnosis
  • Pyelonephritis / drug therapy
  • Pyelonephritis / microbiology*
  • Pyelonephritis / urine
  • Saccharomyces cerevisiae / drug effects
  • Saccharomyces cerevisiae / isolation & purification
  • Saccharomyces cerevisiae / pathogenicity*
  • Treatment Outcome
  • Urinary Tract Infections / blood
  • Urinary Tract Infections / diagnosis
  • Urinary Tract Infections / drug therapy
  • Urinary Tract Infections / microbiology*
  • Urinary Tract Infections / urine
  • Vagina / microbiology
  • Virulence

Substances

  • Antifungal Agents