Approaching the patient with an anterior mediastinal mass: a guide for clinicians

J Thorac Oncol. 2014 Sep;9(9 Suppl 2):S102-9. doi: 10.1097/JTO.0000000000000294.


Anterior mediastinal masses are relatively uncommon, include a wide variety of entities, and often pose a diagnostic challenge for clinicians. In this article, available data is assembled in a clinically oriented manner to develop a structured approach to evaluation of these patients. Attention to age and gender, combined with identification of certain radiographic and clinical characteristics, allows a presumptive diagnosis to be established in most patients. This structure efficiently guides what additional workup is needed.

Publication types

  • Review

MeSH terms

  • Humans
  • Magnetic Resonance Imaging
  • Mediastinal Neoplasms / diagnosis*
  • Mediastinal Neoplasms / diagnostic imaging
  • Mediastinal Neoplasms / pathology
  • Mediastinum / anatomy & histology
  • Mediastinum / pathology
  • Radiography