mimicMe: a web server for prediction and analysis of host-like proteins in microbial pathogens

Bioinformatics. 2015 Feb 15;31(4):590-2. doi: 10.1093/bioinformatics/btu681. Epub 2014 Oct 17.


Summary: mimicMe is a web server for prediction and analysis of host-like proteins (mimics) encoded by microbial pathogens. Users select a host species and any set of pathogen and control proteomes (bacterial, fungal, protozoan or viral) and mimicMe reports host-like proteins that are unique to or enriched among pathogens. Additional server features include visualization of structural similarities between pathogen and host proteins as well as function-enrichment analysis.

Availability and implementation: mimicMe is available at http://mimicme.uwaterloo.ca

Contact: acdoxey@uwaterloo.ca.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Bacteria / genetics*
  • Bacteria / metabolism
  • Bacteria / pathogenicity
  • Bacterial Infections / genetics
  • Bacterial Infections / metabolism
  • Bacterial Infections / microbiology*
  • Bacterial Proteins / genetics*
  • Bacterial Proteins / metabolism
  • Host-Pathogen Interactions
  • Humans
  • Molecular Mimicry / genetics*
  • Molecular Sequence Data
  • Proteome / analysis
  • Sequence Homology, Amino Acid
  • Software*
  • Virulence Factors / genetics*
  • Virulence Factors / metabolism


  • Bacterial Proteins
  • Proteome
  • Virulence Factors