[The results of the pharmacological treatment of attention deficit hyperactivity disorder: evaluation with neuropsychological methods]

Zh Nevrol Psikhiatr Im S S Korsakova. 2014;114(9):19-24.
[Article in Russian]


Objective: To investigate the dynamics of behavioral indicators, attention and memory in children with attention deficit hyperactivity disorder (ADHD) treated with noofen (capsules 250 mg).

Material and method: In an open study, 50 patients were randomized to 2 equal groups: patients of group 1 were treated with noofen (15-20 mg/kg (500-700 mg) per day perorally in 2-3 doses); the control group received low doses of multivitamins. Duration of treatment was one month.

Results: The results of neuropsychological testing revealed the improvement of cognitive functions, including the indicators of self-control, sustained, directed and divided attention, acoustic-verbal memory, to the end of treatment.

Conclusion: The initial positive changes may be the basis for obtaining better clinical results during long-term treatment.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Attention / drug effects
  • Attention Deficit Disorder with Hyperactivity / drug therapy*
  • Attention Deficit Disorder with Hyperactivity / psychology
  • Child
  • Cognition / drug effects
  • Female
  • GABA Agonists / therapeutic use*
  • Humans
  • Male
  • Memory / drug effects
  • Neuropsychological Tests
  • gamma-Aminobutyric Acid / analogs & derivatives*
  • gamma-Aminobutyric Acid / therapeutic use


  • GABA Agonists
  • gamma-Aminobutyric Acid
  • 4-amino-3-phenylbutyric acid