Focal and entrapment neuropathies

Handb Clin Neurol. 2014;126:31-43. doi: 10.1016/B978-0-444-53480-4.00003-5.


Of the many patterns of peripheral nerve disorders in diabetes mellitus (DM), isolated clinical involvement of single nerves, though less common than distal symmetric polyneuropathy and perhaps polyradiculoneuropathy, constitute an important collection of characteristic syndromes. These fall into four anatomical regions of the body: cranial, upper limb, truncal, and lower limb territories. Each of these groups of mononeuropathies has its own ensemble of epidemiologic patterns, clinical presentations, laboratory and radiologic findings, differential diagnosis, management principles and prognosis.

Keywords: Diabetes mellitus; compression neuropathy; focal neuropathy; malignant otitis externa; mononeuropathy; ocular palsy; rhinocerebral mucormycosis.

Publication types

  • Review

MeSH terms

  • Animals
  • Diabetes Mellitus / diagnosis*
  • Diabetes Mellitus / epidemiology
  • Diabetes Mellitus / therapy
  • Diabetic Nephropathies / diagnosis*
  • Diabetic Nephropathies / epidemiology
  • Diabetic Nephropathies / therapy
  • Diagnosis, Differential
  • Humans
  • Nerve Compression Syndromes / diagnosis*
  • Nerve Compression Syndromes / epidemiology
  • Nerve Compression Syndromes / therapy