A Peer-Led HIV Medication Adherence Intervention Targeting Adults Linked to Medical Care but without a Suppressed Viral Load

J Int Assoc Provid AIDS Care. 2015 Sep-Oct;14(5):441-8. doi: 10.1177/2325957414558301. Epub 2014 Nov 20.

Abstract

Background: Non-adherence to antiretroviral (ART) treatment remains a prevalent problem even among the segment of the U.S. HIV population that is 'linked' to medical care.

Methods: Controlled pilot feasibility study with ART experienced adult patients (n = 20) linked to HIV medical care without suppressed viral load. Patients were randomized to a peer-led HIV medication adherence intervention named `Ready' or a time equivalent `healthy eating' control arm. Lay individuals living with HIV were trained to facilitate `Ready'.

Results: Patients had been prescribed a mean of three prior ART regimens. The group randomized to `Ready' had significantly improved adherence. MEMS and pharmacy refill data correlated with viral load log drop. Higher readiness for healthful behavior change correlated with viral load drop and approached significance.

Conclusion: A peer-led medication adherence intervention had a positive impact among adults who had experienced repeated non-adherence to HIV treatment. A larger study is needed to examine intervention dissemination and efficacy.

Keywords: HIV; adherence; intervention; medication; peer led.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Anti-Retroviral Agents / administration & dosage*
  • Early Medical Intervention / methods*
  • Female
  • HIV Infections / drug therapy*
  • HIV Infections / psychology
  • HIV Infections / virology*
  • Health Behavior
  • Humans
  • Male
  • Medication Adherence*
  • Peer Group
  • Pilot Projects
  • Viral Load

Substances

  • Anti-Retroviral Agents