Not merely quiescent: telomeres in quiescent HSCs

Blood. 2014 Nov 20;124(22):3179-80. doi: 10.1182/blood-2014-10-603258.


In this issue of Blood, Wang et al elegantly show that telomere shortening results in DNA damage that induces apoptosis and senescence in quiescent hematopoietic stem cells (HSCs).

Publication types

  • Comment

MeSH terms

  • Animals
  • Apoptosis / physiology*
  • Cellular Senescence / physiology*
  • Hematopoiesis*
  • Hematopoietic Stem Cells / physiology*
  • Telomere Shortening / physiology*