"I Have Remained Strong Because of That Food": Acceptability and Use of Lipid-Based Nutrient Supplements Among Pregnant HIV-Infected Ugandan Women Receiving Combination Antiretroviral Therapy

AIDS Behav. 2015 Aug;19(8):1535-47. doi: 10.1007/s10461-014-0947-0.


We evaluated the acceptability and use of macronutrient supplementation among HIV-infected pregnant Ugandan women receiving antiretroviral therapy in a clinical study (NCT 00993031). We first conducted formative research among 56 pregnant and lactating women to select a supplement regimen. Acceptability and use of the supplementation regimen (35 sachets of lipid-based nutrient supplements (LNS) and 4 or 6 kg of instant soy porridge for the household provided monthly) were evaluated among 87 pregnant women. Organoleptic assessments of LNS were favorable. Participants reported consuming LNS a mean of 6.1 days per week, and adherence to recommended consumption behaviors (e.g. frequency, quantity, not sharing) was >80 %. Few women reported negative social consequences of supplementation. The majority of participants also consumed most of the porridge intended for the household. In sum, LNS was acceptable and used regularly. Larger studies to evaluate physical and psychosocial consequences of LNS during pregnancy among HIV-infected women are warranted.

Trial registration: ClinicalTrials.gov NCT00993031.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Anti-Retroviral Agents / administration & dosage
  • Anti-Retroviral Agents / therapeutic use*
  • Antiretroviral Therapy, Highly Active
  • Breast Feeding
  • Consumer Behavior*
  • Dietary Fats / administration & dosage*
  • Dietary Supplements*
  • Female
  • Follow-Up Studies
  • Food, Fortified*
  • HIV Infections / drug therapy
  • HIV Infections / epidemiology*
  • Humans
  • Interviews as Topic
  • Malnutrition / prevention & control
  • Patient Acceptance of Health Care / statistics & numerical data*
  • Pregnancy
  • Pregnant Women
  • Qualitative Research
  • Uganda / epidemiology


  • Anti-Retroviral Agents
  • Dietary Fats

Associated data

  • ClinicalTrials.gov/NCT00993031