Implications for human adipose-derived stem cells in plastic surgery

J Cell Mol Med. 2015 Jan;19(1):21-30. doi: 10.1111/jcmm.12425. Epub 2014 Nov 26.


Adipose-derived stem cells (ADSCs) are a subset of mesenchymal stem cells (MSCs) that possess many of the same regenerative properties as other MSCs. However, the ubiquitous presence of ADSCs and their ease of access in human tissue have led to a burgeoning field of research. The plastic surgeon is uniquely positioned to harness this technology because of the relative frequency in which they perform procedures such as liposuction and autologous fat grafting. This review examines the current landscape of ADSC isolation and identification, summarizes the current applications of ADSCs in the field of plastic surgery, discusses the risks associated with their use, current barriers to universal clinical translatability, and surveys the latest research which may help to overcome these obstacles.

Keywords: adipose-derived stem cell; lipotransfer; mesenchymal stem cell; stem cell.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Adipose Tissue / cytology*
  • Cell Separation
  • Humans
  • Stem Cell Transplantation
  • Stem Cells / cytology*
  • Surgery, Plastic*