Choroidal neovascularization secondary to choroideremia

Arch Soc Esp Oftalmol. 2015 Jun;90(6):289-91. doi: 10.1016/j.oftal.2014.03.012. Epub 2014 Nov 26.
[Article in English, Spanish]

Abstract

Case report: The case is presented of a 30 year-old man, with night blindness and decreased visual acuity (VA) in both eyes, but more significant in the left eye (LE) of 20/100. Lesions consistent with choroideremia and LE macular hemorrhage was observed in the fundus. CNV was confirmed by OCT. A definitive diagnosis was obtained by genetic study. No treatment was given as the patient did not return. At 6 months there was a regression of CNV with VA 20/25 in the LE.

Conclusions: CNV associated with choroideremia is uncommon. Treatment would antiangiogenic therapy, however spontaneous resolution is possible.

Keywords: Choroidal neovascularization; Choroideremia; Coroideremia; Neovascularización coroidea.

Publication types

  • Case Reports

MeSH terms

  • Adaptor Proteins, Signal Transducing / genetics
  • Adult
  • Angiogenesis Inhibitors / therapeutic use
  • Choroidal Neovascularization / drug therapy
  • Choroidal Neovascularization / etiology*
  • Choroideremia / complications*
  • Choroideremia / genetics
  • Exons / genetics
  • Humans
  • Male
  • Night Blindness / etiology
  • Retinal Hemorrhage / etiology
  • Sequence Deletion
  • Tomography, Optical Coherence

Substances

  • Adaptor Proteins, Signal Transducing
  • Angiogenesis Inhibitors
  • CHM protein, human