Differential expression of the alpha and beta retinoic acid receptors in tissues of the rat

Biochem J. 1989 May 1;259(3):917-9. doi: 10.1042/bj2590917.

Abstract

We have compared the expression of alpha and beta retinoic acid receptors (RAR-alpha and RAR-beta) in different rat tissues. The two cDNA probes for RAR-alpha and RAR-beta each specifically detect two different transcripts. RAR-alpha was expressed in all tissues examined, but, in contrast, the expression of RAR-beta was undetectable in some tissues. The data do not support the idea that RAR-beta is specific to epithelial tissues.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blotting, Northern
  • Carrier Proteins / analysis*
  • DNA Probes
  • Liver / analysis
  • Rats
  • Rats, Inbred Strains
  • Receptors, Retinoic Acid
  • Tretinoin*

Substances

  • Carrier Proteins
  • DNA Probes
  • Receptors, Retinoic Acid
  • Tretinoin